Yet one of the most emotionally complex and interesting manga was a school-based murder mystery about anthropomorphic animals, and that's just wonderful.
BEASTARS, by Paru Itagaki. First published in 2016 and first published in North America in 2019.
PLOT:
At Cherryton Academy, herbivores and carnivores alike study and live together, albeit segregated. It's a tenuous arrangement at best, but the murder of Tem the alpaca brings tensions to a head. At the center of it is Legosi, a tall, awkward wolf and one of the techs in the school drama club. He tries to minimize tension within the club in his own way, but a chance encounter with Haru the dwarf rabbit girl brings out feelings and appetites he's afraid to explore.